Dydrogesterone support in threatened miscarriage
MY El-Zibdeh, LT Yousef - Maturitas, 2009 - Elsevier
MY El-Zibdeh, LT Yousef
Maturitas, 2009•ElsevierINTRODUCTION: The aim of this study was to determine whether dydrogesterone helps to
preserve pregnancy in women with threatened miscarriage. METHODS: 146 women who
were presented with mild or moderate vaginal bleeding during the first trimester of
pregnancy were randomised to receive oral dydrogesterone (10mg bid)(n= 86) or no
treatment (n= 60). Dydrogesterone was continued until 1 week after the bleeding had
stopped. All women received standard supportive care. RESULTS: The incidence of …
preserve pregnancy in women with threatened miscarriage. METHODS: 146 women who
were presented with mild or moderate vaginal bleeding during the first trimester of
pregnancy were randomised to receive oral dydrogesterone (10mg bid)(n= 86) or no
treatment (n= 60). Dydrogesterone was continued until 1 week after the bleeding had
stopped. All women received standard supportive care. RESULTS: The incidence of …
INTRODUCTION
The aim of this study was to determine whether dydrogesterone helps to preserve pregnancy in women with threatened miscarriage.
METHODS
146 women who were presented with mild or moderate vaginal bleeding during the first trimester of pregnancy were randomised to receive oral dydrogesterone (10mg b.i.d.) (n=86) or no treatment (n=60). Dydrogesterone was continued until 1 week after the bleeding had stopped. All women received standard supportive care.
RESULTS
The incidence of miscarriage was significantly lower in the dydrogesterone group than in the untreated group (17.5% vs. 25%; p<0.05). There were no statistically significant differences between the groups with respect to pregnancy complications or congenital abnormalities.
CONCLUSION
Dydrogesterone appears to have beneficial effects in women with threatened miscarriage.
Elsevier