[HTML][HTML] Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2
K Kanno, MK Wu, DS Agate, BJ Fanelli, N Wagle… - Journal of Biological …, 2007 - ASBMB
The Star (steroidogenic acute regulatory protein)-related transfer (START) domain
superfamily is characterized by a distinctive lipid-binding motif. START domains typically
reside in multidomain proteins, suggesting their function as lipid sensors that trigger
biological activities. Phosphatidylcholine transfer protein (PC-TP, also known as StarD2) is
an example of a START domain minimal protein that consists only of the lipid-binding motif.
PC-TP, which binds phosphatidylcholine exclusively, is expressed during embryonic …
superfamily is characterized by a distinctive lipid-binding motif. START domains typically
reside in multidomain proteins, suggesting their function as lipid sensors that trigger
biological activities. Phosphatidylcholine transfer protein (PC-TP, also known as StarD2) is
an example of a START domain minimal protein that consists only of the lipid-binding motif.
PC-TP, which binds phosphatidylcholine exclusively, is expressed during embryonic …