In vivo magnetic resonance spectroscopy of human brain: the biophysical basis of dementia
BD Ross, S Bluml, R Cowan, E Danielsen, N Farrow… - Biophysical …, 1997 - Elsevier
Nuclear magnetic resonance spectroscopy (MRS) in low and medium magnetic fields yields
well-resolved natural abundance proton and decoupled phosphorus spectra from small (1–
10 cc) volumes of brain in vivo in minutes. With this tool, neurochemical research has
advanced through identification and non-invasive assay of specific neuronal—(N-
acetylaspartate), glial (myo-inositol)—markers, energetics and osmolytes, and
neurotransmitters (glutamate, GABA). From these simple measurements, several dozen …
well-resolved natural abundance proton and decoupled phosphorus spectra from small (1–
10 cc) volumes of brain in vivo in minutes. With this tool, neurochemical research has
advanced through identification and non-invasive assay of specific neuronal—(N-
acetylaspartate), glial (myo-inositol)—markers, energetics and osmolytes, and
neurotransmitters (glutamate, GABA). From these simple measurements, several dozen …