A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33–34
KR Vats, C Ishwad, I Singla, A Vats… - Journal of the …, 2006 - journals.lww.com
Congenital anomalies of kidney and urinary tract (CAKUT), including vesico-ureteric reflux
(VUR), are major causes of ESRD in childhood. Herein is reported evidence for a locus on
13q33q34 associated with CAKUT. Deletion mapping of chromosome 13q was performed in
four children with CAKUT using 31 microsatellite markers on peripheral blood genomic DNA
that was obtained from the patients and their parents. mRNA expression of the positional
candidate genes was compared with sequences in electronic databases in silico and also …
(VUR), are major causes of ESRD in childhood. Herein is reported evidence for a locus on
13q33q34 associated with CAKUT. Deletion mapping of chromosome 13q was performed in
four children with CAKUT using 31 microsatellite markers on peripheral blood genomic DNA
that was obtained from the patients and their parents. mRNA expression of the positional
candidate genes was compared with sequences in electronic databases in silico and also …