Congenital solitary functioning kidneys: which ones warrant follow-up into adult life?
V Corbani, GM Ghiggeri… - Nephrology Dialysis …, 2011 - academic.oup.com
V Corbani, GM Ghiggeri, S Sanna-Cherchi
Nephrology Dialysis Transplantation, 2011•academic.oup.comCongenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of
paediatric end-stage renal failure (ESRF)[1, 3]. The clinical spectrum of CAKUT includes a
variety of malformations of the urinary tract. Understanding the rate of progression for the
different CAKUT categories and predicting long-term outcome is critical for a correct clinical
management of these patients and for the transition of care from paediatric to adult
nephrology. Among CAKUT categories, congenital solitary functioning kidney (SFK) has …
paediatric end-stage renal failure (ESRF)[1, 3]. The clinical spectrum of CAKUT includes a
variety of malformations of the urinary tract. Understanding the rate of progression for the
different CAKUT categories and predicting long-term outcome is critical for a correct clinical
management of these patients and for the transition of care from paediatric to adult
nephrology. Among CAKUT categories, congenital solitary functioning kidney (SFK) has …
Congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of paediatric end-stage renal failure (ESRF)[1, 3]. The clinical spectrum of CAKUT includes a variety of malformations of the urinary tract. Understanding the rate of progression for the different CAKUT categories and predicting long-term outcome is critical for a correct clinical management of these patients and for the transition of care from paediatric to adult nephrology.
Among CAKUT categories, congenital solitary functioning kidney (SFK) has been the object of debate whether it constitutes a benign condition or presents a significant risk of progression to ESRF [2–14]. In the present issue of Nephrology Dialysis and Transplantation, Westland et al. report on the results of the KIMONO-study (REF ID pending). The authors analysed a large cohort of 206 children with SFK of congenital origin to identify indicators of renal injury. Among them,
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