How they begin and how they end: classic and new theories for the development and deterioration of congenital anomalies of the kidney and urinary tract, CAKUT
JC POPE IV, JW BROCK III, MC Adams… - Journal of the …, 1999 - journals.lww.com
Congenital anomalies of the kidney and urinary tract (CAKUT) account for more than 50% of
abdominal masses found in neonates and involve some 0.5% of all pregnancies (1, 2).
Despite recent advancements in prenatal diagnosis and early surgical intervention, these
anomalies still remain the primary cause of kidney failure in infants. Notably, the therapeutic
interventions that are available to adults and older children, such as kidney transplantation,
are often not feasible in infants. Ureteropelvic junction (UPJ) obstruction (eg, stenosis or …
abdominal masses found in neonates and involve some 0.5% of all pregnancies (1, 2).
Despite recent advancements in prenatal diagnosis and early surgical intervention, these
anomalies still remain the primary cause of kidney failure in infants. Notably, the therapeutic
interventions that are available to adults and older children, such as kidney transplantation,
are often not feasible in infants. Ureteropelvic junction (UPJ) obstruction (eg, stenosis or …