PURPOSE: Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic
interstitial pneumonia. Numerous inflammatory and pro-fibrotic cytokines may contribute to
the development of this disease. Among these, transforming growth factor beta (TGF-?)
plays a significant role in collagen accumulation by inducing expression and suppressing
degradation of collagens. Undesirable accumulation of collagens results in the development
of numerous diseases, including pulmonary fibrosis. Previous techniques, which were time …