The effect of preseasonal immunotherapy on the production of histamine-refeasing factor (HRF) by mononuclear cells from patients with seasonal asthma: Results of a …
The effect of immunotherapy on the production of histamine-releasing factor (HRF) by
mononuclear cells (MNC) from patients with seasonal asthma was investigated in a double-
blind, placebo-controlled, randomized study. Twenty-four patients with asthma were
randomly divided into a placebo-treated group and a grass pollen-treated group. In vitro
production of HRF by MNCs and the provocative concentration of histamine that causes
20% fall in FEV 1 were measured before and after immunotherapy, and symptoms were …
mononuclear cells (MNC) from patients with seasonal asthma was investigated in a double-
blind, placebo-controlled, randomized study. Twenty-four patients with asthma were
randomly divided into a placebo-treated group and a grass pollen-treated group. In vitro
production of HRF by MNCs and the provocative concentration of histamine that causes
20% fall in FEV 1 were measured before and after immunotherapy, and symptoms were …