Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers
E Ekblad, L Edvinsson, C Wahlestedt, R Uddman… - Regulatory peptides, 1984 - Elsevier
Neuropeptide Y (NPY)-immunoreactive nerve fibers were numerous around arteries and few
around veins. NPY probably co-exists with noradrenaline in such fibers since chemical or
surgical sympathectomy eliminated both NPY and noradrenaline from perivascular nerve
fibers and since double staining demonstrated dopamine-β-hydroxylase, the enzyme that
catalyzes the conversion of dopamine to noradrenaline, and NPY in the same perivascular
nerve fibers. Studies on isolated blood vessels indicated that NPY is not a particularly potent …
around veins. NPY probably co-exists with noradrenaline in such fibers since chemical or
surgical sympathectomy eliminated both NPY and noradrenaline from perivascular nerve
fibers and since double staining demonstrated dopamine-β-hydroxylase, the enzyme that
catalyzes the conversion of dopamine to noradrenaline, and NPY in the same perivascular
nerve fibers. Studies on isolated blood vessels indicated that NPY is not a particularly potent …