ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

G Bindea, B Mlecnik, H Hackl, P Charoentong… - …, 2009 - academic.oup.com
Bioinformatics, 2009academic.oup.com
We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves
biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms
as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term
network. It can analyze one or compare two lists of genes and comprehensively visualizes
functionally grouped terms. A one-click update option allows ClueGO to automatically
download the most recent GO/KEGG release at any time. ClueGO provides an intuitive …
Abstract
Summary: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.
Availability:  http://www.ici.upmc.fr/cluego/cluegoDownload.shtml
Contact:  jerome.galon@crc.jussieu.fr
Supplementary information:  Supplementary data are available at Bioinformatics online.
Oxford University Press