One of the most striking complications in hematologic disease is the development of acute
blood hyperviscosity. Classically, hyperviscosity presents with the triad of bleeding, visual
disturbances, and focal neurologic signs. 1 Hyperviscosity occurs from pathologic elevation
of either the cellular or acellular (protein) fractions of the circulating blood. 2 In cellular
fractions, significant elevation of any of the three primary blood cell lines may lead to clinical
manifestations: erythrocytosis (red blood cells [RBC]), leukocytosis (white blood cells [WBC]) …