[HTML][HTML] Atherosclerosis: the road ahead

CK Glass, JL Witztum - Cell, 2001 - cell.com
Cell, 2001cell.com
Complications of atherosclerosis are the most common causes of death in Western
societies. In broad outline, atherosclerosis can be considered to be a form of chronic
inflammation resulting from interaction between modified lipoproteins, monocyte-derived
macrophages, T cells, and the normal cellular elements of the arterial wall. This
inflammatory process can ultimately lead to the development of complex lesions, or plaques,
that protrude into the arterial lumen. Plaque rupture and thrombosis results in the acute …
Complications of atherosclerosis are the most common causes of death in Western societies. In broad outline, atherosclerosis can be considered to be a form of chronic inflammation resulting from interaction between modified lipoproteins, monocyte-derived macrophages, T cells, and the normal cellular elements of the arterial wall. This inflammatory process can ultimately lead to the development of complex lesions, or plaques, that protrude into the arterial lumen. Plaque rupture and thrombosis results in the acute clinical complications of myocardial infarction and stroke (
cell.com