[PDF][PDF] How steroids steer T cells
C Libert, L Dejager - Cell reports, 2014 - cell.com
C Libert, L Dejager
Cell reports, 2014•cell.comRecent papers from Mahata et al. and Bereshchenko et al. reveal how steroids steer
immune responses by tipping T helper (Th) subset balances and activities. Pregnenolone
produced by Th2 cells mediates immunosuppressive responses, and glucocorticoids
stimulate regulatory T cell development via the induction of GILZ expression.
immune responses by tipping T helper (Th) subset balances and activities. Pregnenolone
produced by Th2 cells mediates immunosuppressive responses, and glucocorticoids
stimulate regulatory T cell development via the induction of GILZ expression.
Recent papers from Mahata et al. and Bereshchenko et al. reveal how steroids steer immune responses by tipping T helper (Th) subset balances and activities. Pregnenolone produced by Th2 cells mediates immunosuppressive responses, and glucocorticoids stimulate regulatory T cell development via the induction of GILZ expression.
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