[HTML][HTML] Autosomal dominant tubulointerstitial kidney disease–umod

AJ Bleyer, K Kidd, M Živná, S Kmoch - 2021 - europepmc.org
AJ Bleyer, K Kidd, M Živná, S Kmoch
2021europepmc.org
Autosomal dominant tubulointerstitial kidney disease–UMOD (ADTKD-UMOD) is
characterized by normal urinalysis and slowly progressive chronic kidney disease (CKD),
usually first noted in the teen years and progressing to end-stage renal disease (ESRD)
between the third and seventh decades. Hyperuricemia is often present from an early age,
and gout (resulting from reduced kidney excretion of uric acid) occurs in the teenage years
in about 8% of affected individuals and develops in 55% of affected individuals over time.
Autosomal dominant tubulointerstitial kidney disease–UMOD (ADTKD-UMOD) is characterized by normal urinalysis and slowly progressive chronic kidney disease (CKD), usually first noted in the teen years and progressing to end-stage renal disease (ESRD) between the third and seventh decades. Hyperuricemia is often present from an early age, and gout (resulting from reduced kidney excretion of uric acid) occurs in the teenage years in about 8% of affected individuals and develops in 55% of affected individuals over time.
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