[HTML][HTML] Distinct Tyrosine Kinase Activation and Triton X-100 Insolubility upon FcγRII or FcγRIIIB Ligation in Human Polymorphonuclear Leukocytes.: IMPLICATIONS …
M Zhou, DM Lublin, DC Link, EJ Brown - Journal of Biological Chemistry, 1995 - ASBMB
Two tyrosine kinase-dependent pathways exist for activation of the respiratory burst by
polymorphonuclear leukocyte (PMN) immunoglobulin G Fc receptors. Direct ligation of
FcγRII activates the respiratory burst, but ligation of the glycan phosphoinositol-linked
FcγRIIIB does not. Instead, this receptor and the integrin complement receptor CR3
synergize in activation of the respiratory burst (Zhou, M.-J., and Brown, EJ (1994) J. Cell Biol.
125, 1407-1416). Here we show that direct ligation of FcγRII leads to activation and Triton X …
polymorphonuclear leukocyte (PMN) immunoglobulin G Fc receptors. Direct ligation of
FcγRII activates the respiratory burst, but ligation of the glycan phosphoinositol-linked
FcγRIIIB does not. Instead, this receptor and the integrin complement receptor CR3
synergize in activation of the respiratory burst (Zhou, M.-J., and Brown, EJ (1994) J. Cell Biol.
125, 1407-1416). Here we show that direct ligation of FcγRII leads to activation and Triton X …