[HTML][HTML] Identification and characterization of a major liver lysophosphatidylcholine acyltransferase

Y Zhao, YQ Chen, TM Bonacci, DS Bredt, S Li… - Journal of Biological …, 2008 - ASBMB
Phosphatidylcholine (PC) is synthesized through the Kennedy pathway, but more than 50%
of PC is remodeled through the Lands cycle, ie the deacylation and reacylation of PC to
attain the final and proper fatty acids within PC. The reacylation step is catalyzed by
lysophosphatidylcholine acyltransferase (LPCAT), and we report here the identification of a
novel LPCAT, which we named LPCAT3. LPCAT3 belongs to the membrane-bound O-
acyltransferase (MBOAT) family and encodes a protein of 487 amino acids with a calculated …