A phase III clinical trial showing limited efficacy of autologous mesenchymal stem cell therapy for spinal cord injury
SK Oh, KH Choi, JY Yoo, DY Kim, SJ Kim… - Neurosurgery, 2016 - journals.lww.com
BACKGROUND: In our previous report, 3 of 10 patients with spinal cord injury who were
injected with autologous mesenchymal stem cells (MSCs) showed motor improvement in the
upper extremities and in activities of daily living. OBJECTIVE: To report on the results of a
phase III clinical trial of autologous MSCs therapy. METHODS: Patients were selected based
on the following criteria: chronic American Spinal Injury Association B status patients who
had more than 12 months of cervical injury, and no neurological changes during the recent 3 …
injected with autologous mesenchymal stem cells (MSCs) showed motor improvement in the
upper extremities and in activities of daily living. OBJECTIVE: To report on the results of a
phase III clinical trial of autologous MSCs therapy. METHODS: Patients were selected based
on the following criteria: chronic American Spinal Injury Association B status patients who
had more than 12 months of cervical injury, and no neurological changes during the recent 3 …