[PDF][PDF] Interleukin-13 is a monocyte chemoattractant
M Magazin, JC Guillemot, N Vita… - European cytokine …, 1994 - researchgate.net
Recombinant human IL-13 is chemotactic for purified human peripheral blood monocytes
Cell migration is stimulated with a typical bell-shaped concentration curve and is maximal at
10 ng/ml. Migration is the result of chemotaxis, and not chemokinesis, as shown by
checkerboard experiments. The chemotactic activity of IL-13 on monocytes is not inhibited
by preincubation of the cells with pertussis toxin but is diminished by preincubation with
protein kinase inhibitors. The related cytokine, IL-4, also stimulates migration of monocytes …
Cell migration is stimulated with a typical bell-shaped concentration curve and is maximal at
10 ng/ml. Migration is the result of chemotaxis, and not chemokinesis, as shown by
checkerboard experiments. The chemotactic activity of IL-13 on monocytes is not inhibited
by preincubation of the cells with pertussis toxin but is diminished by preincubation with
protein kinase inhibitors. The related cytokine, IL-4, also stimulates migration of monocytes …