[HTML][HTML] Inactivation of Corynebacterium glutamicum NCgl0452 and the role of MgtA in the biosynthesis of a novel mannosylated glycolipid involved in lipomannan …

RVV Tatituri, PA Illarionov, LG Dover, J Nigou… - Journal of biological …, 2007 - ASBMB
Mycobacterium tuberculosis PimB has been demonstrated to catalyze the addition of a
mannose residue from GDP-mannose to a monoacylated phosphatidyl-myo-inositol
mannoside (Ac 1 PIM 1) to generate Ac 1 PIM 2. Herein, we describe the disruption of its
probable orthologue Cg-pimB and the chemical analysis of glycolipids and lipoglycans
isolated from wild type Corynebacterium glutamicum and the C. glutamicum:: pimB mutant.
Following a careful analysis, two related glycolipids, Gl-A and Gl-X, were found in the parent …