The ability of malignant cells to evade the immune system, characterized by tumor escape
from both innate and adaptive immune responses, is now accepted as an important hallmark
of cancer. Our research on breast cancer focuses on the active role that tumor infiltrating
lymphocytes play in tumor progression and patient outcome. Toward this goal, we
developed a methodology for the rapid isolation of intact lymphoid cells from normal and
abnormal tissues in an effort to evaluate them proximate to their native state. Homogenates …