[HTML][HTML] The value of protocol biopsies to identify patients with de novo donor-specific antibody at high risk for allograft loss
CA Schinstock, F Cosio, W Cheungpasitporn… - American Journal of …, 2017 - Elsevier
De novo donor-specific antibody (dnDSA) is associated with antibody-mediated rejection
(AMR) and allograft loss, yet the allograft histology associated with dnDSA remains unclear.
The aim of this study was to examine the allograft histology associated with dnDSA in
patients with serial surveillance biopsies. We retrospectively studied adult conventional
solitary kidney transplant recipients from October 2007 to May 2014. The definition of dnDSA
was new donor-specific antibody (DSA) with mean fluorescence intensity (MFI)> 1000. The …
(AMR) and allograft loss, yet the allograft histology associated with dnDSA remains unclear.
The aim of this study was to examine the allograft histology associated with dnDSA in
patients with serial surveillance biopsies. We retrospectively studied adult conventional
solitary kidney transplant recipients from October 2007 to May 2014. The definition of dnDSA
was new donor-specific antibody (DSA) with mean fluorescence intensity (MFI)> 1000. The …