T cells from rejected human kidney allografts respond to heat shock protein 72
K Trieb, B Grubeck-Loebenstein, T Eberl… - Transplant …, 1996 - Elsevier
The immune response to heat shock proteins (hsps) is gaining more and more interest.
Members of the 65 and the 70 kDa hsp families have been shown to be target molecules of
the immune system in autoimmune diseases, in cancer immunity and recently in the
rejection of rat heart allografts. It was therefore the aim of the present study to investigate
whether T cells propagated from two rejected human renal allografts also recognised hsps.
In vivo activated interluekin-2 (IL-2) receptor positive T cells were expanded from renal …
Members of the 65 and the 70 kDa hsp families have been shown to be target molecules of
the immune system in autoimmune diseases, in cancer immunity and recently in the
rejection of rat heart allografts. It was therefore the aim of the present study to investigate
whether T cells propagated from two rejected human renal allografts also recognised hsps.
In vivo activated interluekin-2 (IL-2) receptor positive T cells were expanded from renal …