[HTML][HTML] CD20, AIF-1, and TGF-β in graft-versus-host disease: a study of mRNA expression in histologically matched skin biopsies
JM Wu, CJ Thoburn, J Wisell, ER Farmer, AD Hess - Modern Pathology, 2010 - Elsevier
Graft-versus-host disease is the leading cause of non-relapse mortality after allogeneic bone
marrow transplantation. The cell-mediated immune mechanisms that underlie the
pathogenesis of graft-versus-host disease remain unclear. In this study, 47 skin biopsies
representing graft-versus-host disease grades 0–III, lichenoid, and sclerodermoid were
included from 31 allogeneic bone marrow transplantation recipients. RNA from paraffin-
embedded tissue was harvested. Transcript levels of the following markers were assessed …
marrow transplantation. The cell-mediated immune mechanisms that underlie the
pathogenesis of graft-versus-host disease remain unclear. In this study, 47 skin biopsies
representing graft-versus-host disease grades 0–III, lichenoid, and sclerodermoid were
included from 31 allogeneic bone marrow transplantation recipients. RNA from paraffin-
embedded tissue was harvested. Transcript levels of the following markers were assessed …