Treatment of adult hypophosphatasia with teriparatide
PM Camacho, S Painter, R Kadanoff - Endocrine practice, 2008 - Elsevier
Objective To describe the effects of 24 months of teriparatide therapy in an adult with
hypophosphatasia, which thus far has no established medical treatment. Methods A 75-year-
old woman with hypophosphatasia was treated with ergocalciferol and calcium supplements
for 2 years. She had sustained multiple spontaneous and low-trauma fractures since she
was 10 years old. Baseline biochemical values (and reference ranges) were as follows:
serum total alkaline phosphatase ranged from 14 to 17 U/L (30 to 110), bone-specific …
hypophosphatasia, which thus far has no established medical treatment. Methods A 75-year-
old woman with hypophosphatasia was treated with ergocalciferol and calcium supplements
for 2 years. She had sustained multiple spontaneous and low-trauma fractures since she
was 10 years old. Baseline biochemical values (and reference ranges) were as follows:
serum total alkaline phosphatase ranged from 14 to 17 U/L (30 to 110), bone-specific …