Nonhistone Proteins HMG1 and HMG2 Change the DNA Helical Structure
K Javaherian, LF Liu, JC Wang - Science, 1978 - science.org
K Javaherian, LF Liu, JC Wang
Science, 1978•science.orgTwo chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG1 and
HMG2, reduce the linking number (topological winding number) of a circular DNA if the
covalent closure of the DNA is carried out in their presence. This indicates that these
proteins can either unwind the double helix, or induce a supercoiling of the DNA.
HMG2, reduce the linking number (topological winding number) of a circular DNA if the
covalent closure of the DNA is carried out in their presence. This indicates that these
proteins can either unwind the double helix, or induce a supercoiling of the DNA.
Two chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG1 and HMG2, reduce the linking number (topological winding number) of a circular DNA if the covalent closure of the DNA is carried out in their presence. This indicates that these proteins can either unwind the double helix, or induce a supercoiling of the DNA.
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