Publisher Summary The discovery of ets proteins as transcription factors provided a
framework for understanding the oncogenic potential of ets genes. Ets proteins became a
model system to study the molecular mechanisms of transcriptional control, including how
transcription factors bind DNA, modulate promoter activity, and respond to signaling input.
The current knowledge of the ets proteins is discussed within the framework of this critical
issue. The chapter illustrates the specificity problem and presents possible solutions to the …