CXC chemokines in angiogenesis related to pulmonary fibrosis

RM Strieter, JA Belperio, MP Keane - Chest, 2002 - Elsevier
Angiogenesis, defined as the growth of new capillaries from preexisting vessels, is a
pervasive biological phenomenon that is at the core of many physiologic and pathologic
processes. An opposing balance of angiogenic and angiostatic factors regulates
angiogenesis. Examples of physiologic processes that depend on angiogenesis include
embryogenesis, wound repair, and the ovarian/menstrual cycle. In contrast, chronic
inflammation associated with chronic fibroproliferative disorders as well as growth and …