The cancer stem cell: premises, promises and challenges
H Clevers - Nature medicine, 2011 - nature.com
Nature medicine, 2011•nature.com
Over the last decade, the notion that tumors are maintained by their own stem cells, the so-
called cancer stem cells, has created great excitement in the research community. This
review attempts to summarize the underlying concepts of this notion, to distinguish hard facts
from beliefs and to define the future challenges of the field.
called cancer stem cells, has created great excitement in the research community. This
review attempts to summarize the underlying concepts of this notion, to distinguish hard facts
from beliefs and to define the future challenges of the field.
Abstract
Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.
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