Levels of antibodies against cytomegalovirus and Chlamydophila pneumoniae are increased in early onset pre-eclampsia

P von Dadelszen, LA Magee, M Krajden… - BJOG: an international …, 2003 - Elsevier
OBJECTIVE: The origins of pre-eclampsia/eclampsia lie in a mismatch between feto-
placental demands and utero-placental supply, a situation that also arises in normotensive
intrauterine growth restriction (IUGR). Could reactivated chronic infection be both a trigger
for these differential maternal responses to the same underlying pathology and a link
between pre-eclampsia and its attendant lifelong risks of atherosclerosis? DESIGN: Nested
case–control study. SETTING: Tertiary obstetric centre. POPULATION: Cases of pre …