Phasic responses in dorsal raphe serotonin neurons to noxious stimuli
JV Schweimer, MA Ungless - Neuroscience, 2010 - Elsevier
JV Schweimer, MA Ungless
Neuroscience, 2010•ElsevierSerotonin is widely implicated in aversive processing. It is not clear, however, whether
serotonin neurons encode information about aversive stimuli. We found that, in the dorsal
raphe of anesthetized rats, most neurochemically-identified clocklike serotonin neurons
were phasically excited by noxious footshocks, whereas most bursting serotonin neurons
were inhibited. These results suggest that discrete groups of serotonin neurons differentially
code for aversive stimuli.
serotonin neurons encode information about aversive stimuli. We found that, in the dorsal
raphe of anesthetized rats, most neurochemically-identified clocklike serotonin neurons
were phasically excited by noxious footshocks, whereas most bursting serotonin neurons
were inhibited. These results suggest that discrete groups of serotonin neurons differentially
code for aversive stimuli.
Serotonin is widely implicated in aversive processing. It is not clear, however, whether serotonin neurons encode information about aversive stimuli. We found that, in the dorsal raphe of anesthetized rats, most neurochemically-identified clocklike serotonin neurons were phasically excited by noxious footshocks, whereas most bursting serotonin neurons were inhibited. These results suggest that discrete groups of serotonin neurons differentially code for aversive stimuli.
Elsevier