[HTML][HTML] The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity
K Takeyama, RCT Aguiar, L Gu, C He… - Journal of Biological …, 2003 - ASBMB
Members of the DTX (Deltex) family act as Notch signaling modifiers and may also regulate
transcription through interactions with specific transcription factors. DTX proteins have a
basic N terminus; a central proline-rich region; and a C-terminal RING finger domain, a motif
often found in ubiquitin-protein isopeptide ligases (E3). Recently, we identified and
characterized a unique diffuse large B-cell lymphoma risk-related gene named BAL (B
aggressive lymphoma). Using a yeast two-hybrid screen for BAL-binding partners, we have …
transcription through interactions with specific transcription factors. DTX proteins have a
basic N terminus; a central proline-rich region; and a C-terminal RING finger domain, a motif
often found in ubiquitin-protein isopeptide ligases (E3). Recently, we identified and
characterized a unique diffuse large B-cell lymphoma risk-related gene named BAL (B
aggressive lymphoma). Using a yeast two-hybrid screen for BAL-binding partners, we have …