Macrocytic anemia, thrombocytosis and nonlobulated megakaryocytes: The 5q-syndrome, a distinct entity
T Mahmood, WA Robinson, RD Hamstra… - The American Journal of …, 1979 - Elsevier
The clinical, hematologic and histologic characteristics of six patients with refractory anemia
with deletion of the long arm of chromosome# 5 are described. These patients had a distinct
hematologic picture with macrocytic anemia of mild to moderate severity, normal to low
leukocyte count and increased platelet count. The long arm of chromosome# 5 was deleted
in the majority of bone marrow metaphases. The main cause of anemia was
underproduction with decreased erythroid precursors in the bone marrow and no increase in …
with deletion of the long arm of chromosome# 5 are described. These patients had a distinct
hematologic picture with macrocytic anemia of mild to moderate severity, normal to low
leukocyte count and increased platelet count. The long arm of chromosome# 5 was deleted
in the majority of bone marrow metaphases. The main cause of anemia was
underproduction with decreased erythroid precursors in the bone marrow and no increase in …