[CITATION][C] Sequential stimulations by oestrogen of nuclear RNA synthesis and DNA-dependent RNA polymerase activities in rat uterus

TH Hamilton, CC Widnell, JR Tata - … et Biophysica Acta (BBA)-Nucleic Acids …, 1965 - Elsevier
It has been shown that the biological action of oestrogen in the uterus of the ovariectomized
rat is preceded by a stimulation of rapidly-labelled nuclear RNA synthesis in vivol, 2 and of
DNA-dependent RNA polymerase (EC 2.7. 7.6) assayed in preparations from isolated nuclei
3. Before any attempt can be made to determine the nature of the primary site of action for
this hormone, it is essential to determine the sequence of events initiated by the hormone.
WIDNELL AND TATA 4 have described two DNA-dependent RNA polymerase reactions in …