[HTML][HTML] Alteration of circulating type 2 follicular helper T cells and regulatory B cells underlies the comorbid association of allergic rhinitis with bronchial asthma
R Kamekura, K Shigehara, S Miyajima, S Jitsukawa… - Clinical …, 2015 - Elsevier
Allergic rhinitis (AR), the most common allergic disorder of the airway, is often accompanied
by bronchial asthma. However, little is known about the mechanism by which AR advances
to AR comorbid with bronchial asthma (AR+ Asthma). To determine the pathophysiologic
features of AR and AR+ Asthma, we examined subsets of follicular helper T (Tfh) cells and
regulatory B (Breg) cells in peripheral blood from AR and AR+ Asthma patients. The results
showed polarization of Tfh2 cells within Tfh cell subsets in both AR and AR+ Asthma cases …
by bronchial asthma. However, little is known about the mechanism by which AR advances
to AR comorbid with bronchial asthma (AR+ Asthma). To determine the pathophysiologic
features of AR and AR+ Asthma, we examined subsets of follicular helper T (Tfh) cells and
regulatory B (Breg) cells in peripheral blood from AR and AR+ Asthma patients. The results
showed polarization of Tfh2 cells within Tfh cell subsets in both AR and AR+ Asthma cases …