[PDF][PDF] Pulmonary hypertension in sickle cell disease
MT Lee, EB Rosenzweig, MS Cairo - Clin Adv Hematol Oncol, 2007 - researchgate.net
MT Lee, EB Rosenzweig, MS Cairo
Clin Adv Hematol Oncol, 2007•researchgate.netPulmonary hypertension (PH), a disorder characterized by elevated pulmonary artery
pressure and pulmonary vascular resistance, is an increasingly recognized complication of
sickle cell disease (SCD), with a prevalence of approximately 30% in adult patients. It
confers a high risk of death, with 2-year mortality rates of 40–50%, even at modest
elevations of pulmonary pressures. The pathogenesis of PH complicating
pressure and pulmonary vascular resistance, is an increasingly recognized complication of
sickle cell disease (SCD), with a prevalence of approximately 30% in adult patients. It
confers a high risk of death, with 2-year mortality rates of 40–50%, even at modest
elevations of pulmonary pressures. The pathogenesis of PH complicating
Abstract
Pulmonary hypertension (PH), a disorder characterized by elevated pulmonary artery pressure and pulmonary vascular resistance, is an increasingly recognized complication of sickle cell disease (SCD), with a prevalence of approximately 30% in adult patients. It confers a high risk of death, with 2-year mortality rates of 40–50%, even at modest elevations of pulmonary pressures. The pathogenesis of PH complicating
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