Influence of endotoxin on adipose tissue metabolism

JA Spitzer, AGB Kovach, S Rosell, P Sandor… - … and Metabolic Aspects …, 1973 - Springer
JA Spitzer, AGB Kovach, S Rosell, P Sandor, JJ Spitzer, R Storck
Neurohumoral and Metabolic Aspects of Injury: Proceeding of the IUPS Satellite …, 1973Springer
Adipose tissue representa a relatively large tissue mass, about 15% of body weight,
receiving a substantial portion of the cardiac output. Regional vasomotor adjustments in this
vascular bed, therefore, are very likely to influence the “overall” hemodynamics of the
animal. In addition, the mobilization of free fatty acids (FFA) from the energy rich triglyceride
stores of adipose tissue is also dependent on an adequate blood supply. Since in endotoxic
shock vascular responses are drastically altered, it became of interest to study the effect of …
Abstract
Adipose tissue representa a relatively large tissue mass, about 15% of body weight, receiving a substantial portion of the cardiac output. Regional vasomotor adjustments in this vascular bed, therefore, are very likely to influence the “overall” hemodynamics of the animal. In addition, the mobilization of free fatty acids (FFA) from the energy rich triglyceride stores of adipose tissue is also dependent on an adequate blood supply. Since in endotoxic shock vascular responses are drastically altered, it became of interest to study the effect of endotoxin administration on adipose tissue metabolism.
Springer