[PDF][PDF] Starving Intestinal Inflammation with the amino acid sensor GCN2

XS Revelo, S Winer, DA Winer - Cell Metabolism, 2016 - cell.com
Cell Metabolism, 2016cell.com
Starving Intestinal Inflammation with the Amino Acid Sensor GCN2 Page 1 testosterone
secretion could constitute another layer of regulation that affects b cell function. The study by
Navarro et al. (2016) sets the stage for further exploration of the role of androgens in b cells and
the pathogenesis of type 2 diabetes. ACKNOWLEDGMENTS MS is supported by the National
Institutes of Health, Juvenile Diabetes Research Foundation (JDRF), Helmsley Charitable Trust,
and the California Institute of Regenerative Medicine. MW is the recipient of a JDRF postdoctoral …
Metabolic stressors are emerging as important controls over immune system function. In a recent paper, Ravindran et al. (2016) uncovered a novel mechanism by which an amino acid sensing pathway controls inflammation in the gut.
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