C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: results from the MONICA Augsburg cohort study, 1984-1998

B Thorand, H Löwel, A Schneider, H Kolb… - Archives of internal …, 2003 - jamanetwork.com
Background Previous studies have suggested that low-grade systemic inflammation is
involved in the pathogenesis of type 2 diabetes mellitus. Objective To investigate the
association between C-reactive protein (CRP), the classic acute-phase protein, and incident
type 2 diabetes mellitus among middle-aged men. Methods A total of 2052 initially
nondiabetic men aged 45 to 74 years who participated in 1 of the 3 MONICA (Monitoring of
Trends and Determinants in Cardiovascular Disease) Augsburg surveys between 1984 and …