[HTML][HTML] Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice

A Ejaz, D Wu, P Kwan, M Meydani - The Journal of nutrition, 2009 - Elsevier
Angiogenesis is necessary for the growth of adipose tissue. Dietary polyphenols may
suppress growth of adipose tissue through their antiangiogenic activity and by modulating
adipocyte metabolism. We investigated the effect of curcumin, the major polyphenol in
turmeric spice, on angiogenesis, adipogenesis, differentiation, apoptosis, and gene
expression involved in lipid and energy metabolism in 3T3-L1 adipocyte in cell culture
systems and on body weight gain and adiposity in mice fed a high-fat diet (22%) …