Adipose tissue is a highly active endocrine organ, secreting bioactive molecules,
adipokines, into the circulation. Obesity results in dysregulated adipokine secretion,
contributing to pathophysiologies associated with this disorder, including insulin resistance
and cardiovascular disease. OBJECTIVES: To establish whether resistin, a novel bioactive
molecule produced by murine adipose tissue, and implicated in insulin resistance in
rodents, can induce angiogenic responses in aortic tissues and endothelial cells in vitro, and …