Sepsis is systemic expression of a generalized activation of the host's innate immunity as a
result of varied types of insults. This expression involves a cellular inflammatory response
that has both proinflammatory and antiinflammatory components, the primary trigger for
which is an intracellular oxidative stress, induced by receptor-mediated transmembrane
signal transduction or direct noxious injury. Sepsis reflects the interaction between pro-and
anti-inflammatory intracellular mechanisms, the uncontrolled activation of which leads to cell …