[HTML][HTML] Interference of H2O2 with stimulus-secretion coupling in mouse pancreatic β-cells
P Krippeit-Drews, C Krämer, S Welker… - The Journal of …, 1999 - ncbi.nlm.nih.gov
P Krippeit-Drews, C Krämer, S Welker, F Lang, HPT Ammon, G Drews
The Journal of physiology, 1999•ncbi.nlm.nih.govWe have reported previously that in mouse pancreatic β-cells H 2 O 2 hyperpolarizes the
membrane and increases the ATP-sensitive K+ current recorded in the perforated patch
configuration of the patch-clamp technique. The present study was undertaken to elucidate
the underlying mechanisms.
membrane and increases the ATP-sensitive K+ current recorded in the perforated patch
configuration of the patch-clamp technique. The present study was undertaken to elucidate
the underlying mechanisms.
Abstract
1. We have reported previously that in mouse pancreatic β-cells H 2 O 2 hyperpolarizes the membrane and increases the ATP-sensitive K+ current recorded in the perforated patch configuration of the patch-clamp technique. The present study was undertaken to elucidate the underlying mechanisms.
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