[HTML][HTML] Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9

RE Mansfield, CA Musselman, AH Kwan… - Journal of Biological …, 2011 - ASBMB
A major challenge in chromatin biology is to understand the mechanisms by which
chromatin is remodeled into active or inactive states as required during development and
cell differentiation. One complex implicated in these processes is the nucleosome
remodeling and histone deacetylase (NuRD) complex, which contains both histone
deacetylase and nucleosome remodeling activities and has been implicated in the silencing
of subsets of genes involved in various stages of cellular development. Chromodomain …