Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers
J Barnes, MD Mayes - Current opinion in rheumatology, 2012 - journals.lww.com
J Barnes, MD Mayes
Current opinion in rheumatology, 2012•journals.lww.comPrevalence and incidence of SSc appears to be greater in populations of European ancestry
and lower in Asian groups. Exposure to silica dust appears to be an environmental trigger,
but this only accounts for a small proportion of male cases. Evidence for increased risk of
neoplasia is suggestive, but the magnitude of the risk and the types of malignancies vary
among reports.
and lower in Asian groups. Exposure to silica dust appears to be an environmental trigger,
but this only accounts for a small proportion of male cases. Evidence for increased risk of
neoplasia is suggestive, but the magnitude of the risk and the types of malignancies vary
among reports.
Summary
Prevalence and incidence of SSc appears to be greater in populations of European ancestry and lower in Asian groups. Exposure to silica dust appears to be an environmental trigger, but this only accounts for a small proportion of male cases. Evidence for increased risk of neoplasia is suggestive, but the magnitude of the risk and the types of malignancies vary among reports.
Lippincott Williams & Wilkins