Role of the actin cytoskeleton in ischemia-induced cell injury and repair

BA Molitoris, J Leiser, MC Wagner - Pediatric nephrology, 1997 - Springer
BA Molitoris, J Leiser, MC Wagner
Pediatric nephrology, 1997Springer
This paper reviews the role of the actin cytoskeleton in the establishment and maintenance
of surface membrane structure and function in all epithelial cells. It describes in detail certain
interactions between the actin cytoskeleton and the surface membrane. Recent studies
show that ischemia and/or ATP depletion will rapidly disrupt the actin cytoskeleton, an
important event in ischemia-induced cell injury. Finally, the review examines specific
functional and structural interactions between the actin cytoskeleton and the surface …
Abstract
This paper reviews the role of the actin cytoskeleton in the establishment and maintenance of surface membrane structure and function in all epithelial cells. It describes in detail certain interactions between the actin cytoskeleton and the surface membrane. Recent studies show that ischemia and/or ATP depletion will rapidly disrupt the actin cytoskeleton, an important event in ischemia-induced cell injury. Finally, the review examines specific functional and structural interactions between the actin cytoskeleton and the surface membrane.
Springer