[HTML][HTML] Nuclear hormone receptors in T lymphocytes

A Winoto, DR Littman - Cell, 2002 - cell.com
Cell, 2002cell.com
Among the numerous steroid and orphan nuclear receptors encoded within mammalian
genomes, several are involved in regulating immune system functions. We review here
recent studies on the glucocorticoid receptor and the orphan receptors Nur77 and RORγ.
These molecules play key roles in the development and the effector functions of T
lymphocytes.
Abstract
Among the numerous steroid and orphan nuclear receptors encoded within mammalian genomes, several are involved in regulating immune system functions. We review here recent studies on the glucocorticoid receptor and the orphan receptors Nur77 and RORγ. These molecules play key roles in the development and the effector functions of T lymphocytes.
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