[HTML][HTML] EBV PCR in the diagnosis and monitoring of posttransplant lymphoproliferative disorder: results of a two-arm prospective trial
DE Tsai, L Douglas, C Andreadis, DT Vogl… - American journal of …, 2008 - Elsevier
While EBV PCR is used in the management of PTLD, the optimal primer set, relative
importance of intracellular versus free plasma EBV, and the baseline profile in an organ
transplant population remains unclear. We performed a prospective 2-arm trial utilizing an
EBV PCR panel measuring LMP-1, EBER-1 and EBNA-1 in both free plasma as well as
intracellular whole blood. Control Arm A consisted of 31 lung transplant patients and Arm B
consisted of 35 transplant patients being evaluated for possible PTLD. In Arm A, 1/31 (3%) …
importance of intracellular versus free plasma EBV, and the baseline profile in an organ
transplant population remains unclear. We performed a prospective 2-arm trial utilizing an
EBV PCR panel measuring LMP-1, EBER-1 and EBNA-1 in both free plasma as well as
intracellular whole blood. Control Arm A consisted of 31 lung transplant patients and Arm B
consisted of 35 transplant patients being evaluated for possible PTLD. In Arm A, 1/31 (3%) …