Eosinophils, multifunctional cells that contribute to both innate and adaptive immunity, are
involved in the initiation, propagation, and resolution of immune responses, including tissue
repair. They achieve this multifunctionality by expression of a diverse set of activation
receptors, including those that directly recognize pathogens and opsonized targets, and by
their ability to store and release preformed cytotoxic mediators that participate in host
defense, to produce a variety of de novo pleotropic mediators and cytokines, and to interact …