Initiation and use of propranolol for infantile hemangioma: report of a consensus conference

BA Drolet, PC Frommelt, SL Chamlin, A Haggstrom… - …, 2013 - publications.aap.org
Infantile hemangiomas (IHs) are common neoplasms composed of proliferating endothelial-
like cells. Despite the relative frequency of IH and the potential severity of complications,
there are currently no uniform guidelines for treatment. Although propranolol has rapidly
been adopted, there is significant uncertainty and divergence of opinion regarding safety
monitoring, dose escalation, and its use in PHACE syndrome (PHACE= posterior fossa,
hemangioma, arterial lesions, cardiac abnormalities, eye abnormalities; a cutaneous …