[HTML][HTML] Stress-inducible protein p8 is involved in several physiological and pathological processes
S Goruppi, JL Iovanna - Journal of biological chemistry, 2010 - ASBMB
p8 (NUPR1 (nuclear protein-1), Com1 (candidate of metastasis-1)) is a protein related to the
high mobility group of transcriptional regulators. It is a key player in the cellular stress
response and is involved in metastasis. p8 was first identified as a gene induced in
pancreatitis but has been since found overexpressed in several cancers and pathological
conditions. Despite its small size and apparently simple structure, p8 functions in several
biochemical and genetic pathways, and its expression is crucial for in vivo metastasis in …
high mobility group of transcriptional regulators. It is a key player in the cellular stress
response and is involved in metastasis. p8 was first identified as a gene induced in
pancreatitis but has been since found overexpressed in several cancers and pathological
conditions. Despite its small size and apparently simple structure, p8 functions in several
biochemical and genetic pathways, and its expression is crucial for in vivo metastasis in …